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TABLE OF CONTENTS

HANC ANNOUNCEMENTS

NETWORK ANNOUNCEMENTS

HANC PROGRAM UPDATES

CONFERENCES AND MEETINGS

 
 
DAIDS Welcomes Questions, Comments, Suggestions
January 2026

In early January, HANC hosted a public, virtual meet-and-greet with Dr. Bob Eisinger, the Acting Director of the Division of AIDS at the National Institute of Allergy and Infectious Diseases (DAIDS).

As part of the ongoing commitment to community engagement and public transparency, DAIDS welcomes questions, comments, and suggestions via email: DAIDSGeneral@mail.nih.gov.
 

REFLECTIONS ON NATIONAL BLACK HIV/AIDS AWARENESS DAY
National Black HIV/AIDS Awareness Day (NBHAAD) is dedicated to raising awareness about the disproportionate impact of HIV on Black and African American communities. First observed in 1999, NBHAAD highlights the importance of community involvement and improved access to HIV education, prevention, testing, and treatment services. HANC called upon a few treasured collaborators to share their thoughts on the day.
CLIFFORD CASTLEBERRY, M.S. 
Program Manager
AIDS United 

"National Black HIV/AIDS Awareness Day is about showing up for our community while also reflecting on the systems that shape our health. This awareness day highlights how HIV continues to disproportionately impact Black people and underscores the need for equitable access to quality care, prevention options like PrEP, and education. By increasing awareness, we can reduce stigma, encourage testing, and improve health outcomes. On NBHAAD, I encourage us to know our status, engage with prevention or treatment on our own terms, and take part in the collective effort to end the HIV epidemic."




DAZON DIXON DIALLO
Founder
SisterLove
“Raise your hand if you haven’t heard this one: African Americans, the Black Diaspora and Black Africans on the Continent continue to bear a disparate proportion of the HIV epidemic. We have spent the better part of 44 years shouting at the rooftops and marching in the streets to raise awareness of this unacceptable reality. But raising awareness of HIV - independent of racial and ethnic injustices, void of economic and health disparities, absent of critical analysis of historical oppression, and marginalized from the center of power and resources – sustaining exclusive focus on HIV is obviously not enough. On this National Black HIV AIDS Awareness Day, we must sound the intersectional clarion to be sure that all communities understand the connections between militarizing immigration laws, profiling people based on skin color and language, and creating scarcity in basic needs and safety nets are all part of understanding that HIV in the Black Community is about more than a virus – it is about justice, divsersity, dignity, inclusion and yes, it is about equity to the margins and beyond.”

CHRISTOPHER HUCKS-ORTIZ, MPH 
Public Health Professional
“Engage, Educate, Empower: Uniting to End HIV/AIDS in Black Communities:

Each year on February 7th we recognize National Black HIV/AIDS Awareness Day (NBHAAD).  On this day we take a moment to raise awareness of the impact(s) of HIV/AIDS on Black communities across the nation.  This year, given the current political and economic climate has and its impact on the work of HIV/AIDS Prevention, Care, Treatment, and Research, it is even more critical that we “engage, educate, and empower” ourselves and our communities.

CDC data (2021) shows 40% of new diagnosis among African American/Black people although this population accounts for only 13 percent of the total population.  These disparities exist even more so in the Southern US where 49 percent of new infections are among Black communities.  And so today I ask you regardless of sociopolitical perspectives what are our obligations to the Black communities and people; communities where there is still a need for us to show up as our most compassionate selves and address the full spectrum of HIV prevention and treatment, linkages to care and clinical research.  Determine what and how you will show up and then pledge to do so.  Each of us can make a difference if we come together.  Will you join me?" 

TYPHANYE V. DYER, PhD, MPH
Associate Professor
University of Maryland
"National Black HIV/AIDS Awareness Day is a day that we often commemorate with thoughts and feelings of reflection on how far we’ve come in the fight against HIV/AIDS. These reflections can often bring feelings of melancholy but also happiness. This season, it’s even more imperative to reflect and ACT, as our very existence as warriors in the struggle is threatened from every angle imaginable.


So, instead of reflecting on how far we’ve come or how much further we have to go, I would like to take time to reflect on the NOW and be present. While happiness is often fleeting and due to extrinsic factors (factors outside of ourselves), joy is intrinsic, deep, sustained and more than “just” a smile. Joy is nurtured by LOVE…even during hard times. So…what brings you joy?" 

HAROLD J. PHILLIPS, MRP
Chief Executive Officer
NMAC
"For me, National Black HIV/AIDS Awareness Day is a moment of personal and public reckoning. As a Black gay man living with HIV for over 20 years, and as CEO of NMAC, I see clearly how far we’ve come. We achieved a 12% decrease in new cases between 2018 and 2022, proving that focused, bipartisan investment works.

However, the work isn’t finished. To me, this day signifies the enduring strength of our community. It is a reminder that we must hold our leaders accountable to the promise of ending this epidemic. We are too close to the finish line to turn back now."





 
 
READ "FAKE DRUGS, REAL CONCERNS"
 

 
The NEXUS Spotlight
 
 
 

Raphael J. Landovitz MD MSc
Co-Principal Investigator
(with Sinead Delany-Moretlwe) of the HPTN

University of California, Los Angeles, CA
In December 2025, Dr. Landovitz assumed the role of co-principal investigator of the HIV Prevention Trials Network (HPTN). From HPTN's website: "As one of the protocol chairs for HPTN 077 and HPTN 083, Dr. Landovitz helped lead the NIH-funded trials that supported the 2021 FDA approval of long-acting injectable cabotegravir for HIV pre-exposure prophylaxis (PrEP)". Dr. Landovitz clearly leads in scientific integrity, and we can't wait to see where he leads the HPTN in this new role.

Describe your current work in HIV research.

I come from a background of providing HIV care and treatment, and developed an interest in prevention when I worked on the hospital PEP service during my training as an advanced HIV Fellow at Brigham and Women’s Hospital in Boston.   After working to support technical assistance for PEPFAR in Vietnam, I had a brief detour into drug development in the pharmaceutical industry before beginning my academic clinical research career at UCLA.  I am still clinically active with providing HIV and STI care and prevention services, and am extremely passionate about developing a broad menu of HIV prevention choices, and supporting their implementation and equitable use for all.


What goals do you have for the coming year?

I think my number one goal for this first year of leading the HPTN is to be a good listener.   Sinead and I are working very hard to fill the (very large!) shoes of Drs. Cohen and El-Sadr, and to listen to the HPTN investigators, partners, stakeholders, and collaborators, to hear what people think is going well for the network, and what we can improve on.   We also are working very hard to make sure we make prevention research available to all communities, and answer the questions most important to those communities.   We also have a really important role in making sure the work does not falter - the work is too important to allow it to falter; we have to be smart, efficient, and navigate complicated headwinds, but we will emerge stronger and wiser than before in the end.

What motivates you in this work?

I am constantly inspired by the HPTN community (everyone!) and the dedication, passion, and commitment that everyone brings to the work every day, no matter what the adversity, no matter how challenging the problem.   It is absolutely awe-inspiring, and I draw strength from that knowledge.

What can others do to support HIV research?
We need activism more than ever;  progress against the HIV epidemic has long been powered by the heroic activism of those with, affected by, and/or at-risk for HIV.  This is not the time to be silent.   We are all in this together.

What are your passions outside of work?

I think anyone within the HPTN or outside it knows that I am an encyclopedia of musical theater.  I have no talent, but I am a huge fan. 

What fictional character best represents you?

Paddington the Bear.

Tell us something that most people wouldn’t know about you. 

There is a very important and exact science to the New York specialty cookie (I’m from New York originally) the “Black and White” cookie.  I have very specific feelings about the optimal construction and properties of that type of cookie.   I don’t think most people are that invested in the specifics of a cookie.

Clearly scientific integrity is paramount for Dr. Landovitz - be it cutting-edge HIV research or concocting the perfect "Black and White" cookie. Dr. Landovitz's commitment to HIV prevention and care is music to our ears, apropos of a zealous musical theater lover.

 
 
 
 
PRESS RELEASE

On January 9, 2025, ACTG announced the opening of the IPACE-HIV study (Improving Physical Ability and Cellular Senescence Elimination in HIV), also known as A5426. IPACE-HIV is a phase 2, double-blind, randomized study evaluating the safety, tolerability, and efficacy of dasatinib and quercetin in improving physical function outcomes in people living with HIV who are frail or exhibit symptoms that they may become frail. Click below to read the release in full.

ACTG Launches IPACE-HIV to Study Frailty Intervention

 
 
HPTN Study Evaluating On-Demand PrEP Achieves 100% Enrollment Goal

HPTN 106 (REV UP), evaluating the use of on-demand rectal douche and oral HIV pre-exposure prophylaxis, has completed its target enrollment of 150 participants across 8 Division of AIDS (DAIDS) research sites in the United States. This milestone marks an important step in evaluating additional HIV prevention tools and options for communities impacted by HIV. Reaching full enrollment is a significant achievement, made possible by the efforts of research sites, study teams, and participants.


HPTN 106 (REV UP) is a randomized, crossover study designed to assess the extended safety and acceptability of a tenofovir (TFV) rectal microbicide douche, advancing it along the development pathway as an on-demand HIV PrEP strategy. More information about HPTN 106 (REV UP) can be found on ClinicalTrials.gov under the ID NCT06560684.
No updates at this time.
 
Study Updates

  • IMPAACT 2024 opened to accrual as of 27 January 2026. The study is designed to evaluate daily rifapentine combined with isoniazid for tuberculosis prevention in children (less than 13 years old) with and without HIV.  The study is planned to take place at 10 sites in Botswana, Kenya, Thailand, Uganda, and Zimbabwe.

  • IMPAACT 2037 began enrolling as of 5 January 2026. The study is evaluating two broadly neutralizing antibodies (bNAbs) among infants at high risk for HIV. Congratulations to the Bronx-Lebanon Hospital (Site 5114) for enrolling the first mother-infant pair into the study. The study is taking place at 16 sites in Brazil, Kenya, US, and Zimbabwe.

IMPAACT at CROI 2026

Colleagues will be representing the IMPAACT Network at CROI 2026 by presenting 18 abstracts with data from 12 studies (2 as oral presentations, 1 as a poster with themed discussion, and 15 as poster presentations). Presentations include data from IMPAACT P1115, IMPAACT 2042/Tatelo Plus, IMPAACT 2010/VESTED, IMPAACT 2016, and others.

Once the embargo has been lifted and the conference has concluded, presentations and posters will be available on the IMPAACT website.

Annual Meeting

The IMPAACT Network Annual Meeting will take place virtually from 9-11 June. The Community Plenary dates are forthcoming. All details will be shared on the Annual Meeting page.
 
 
Behavioral and Social Sciences
 
Kathleen Pescasio
HANC Cross-Network
Project Manager
The Behavioral Science Consultation Group discussed anticipated roles for behavioral and social sciences within the networks moving forward, including considerations related to implementation science. The group also shared perspectives on how the role of the BSCG may evolve over the next year.

Community Coordination
 
Murph Fuentes
HANC
Project Coordinator
Russell Campbell
HANC Director
Community Partners (CP): Community Partners has started planning its activities for 2026, based on their 2026 work plan. An ad hoc working group is being formed to create a TB White Paper, outlining the work and collaboration between CP and CRAG that explores the complex relationship between HIV and TB. The Community Research Advisors Group (CRAG) is an international, community-based advisory body that works to ensure the meaningful representation and engagement of affected communities in research conducted by the United States Centers for Disease Control’s Tuberculosis Trials Consortium (TBTC).


Cross-Network Coordination
 
Kathleen Pescasio
HANC Cross-Network
Project Manager
The Communications Working Group (CWG) shared network updates and plans for the new year, including conference activities, annual meetings, and operational transitions. Members also discussed expectations around the upcoming NIH re-competition and continued cross-network coordination.


The Cross-Network Data Management Center Working Group (DMCWG)  recently convened to discuss regulatory and data transfer updates for Zimbabwe sites. Members also shared updates related to system upgrades, centralized monitoring coordination, and efforts to improve data review and efficiency.

Laboratory Coordination
 
Tyler Brown
HANC Laboratory
Project Manager
The CNCPL Discussion Group met in January and discussed troubleshooting autosampler injection issues, approaches to manual integration procedures, and recent changes to areas covered during CLIA inspections.

The Legacy Project
 
Brian Minalga
HANC
Deputy Director
Gabriella Olague
Legacy
Project Coordinator
 
1/14: Brian met with the Fred Hutch Office of Community Outreach and Engagement to present on the Legacy Project’s recent publication in the American Journal of Bioethics, The Representative Studies Rubric: A Tool for Diversity in Clinical Trials. Check out one of Brian’s slides on why representativeness matters in research (spoiler alert: it’s for science and ethics, not politics!):

1/30: Brian met with the NIH Office of AIDS Research HIV/AIDS Clinical Trials Networks External Review Working Group to present on the stakeholder priorities identified and collated in 2025 through the Legacy Project, which cover five main categories: scientific priorities, funding, participant considerations, community engagement, and workforce development. The OAR working group is in the process of developing recommendations for the future of the Networks and will publish these recommendations in the coming months.


2/22-25: Brian will be in Denver, CO to participate in CROI. You'll find Brian at the Community CROI Breakfast Club on Tuesday, February 24 from 7 to 8 a.m. Mountain Time where Brian is an invited speaker on the topic, Counting and Caring for Trans and Gender Non-Binary Individuals, a symposium featuring Jade Ghosn, Stefan Baral, Asa Radix, and Rena Janamnuaysook that will take place later that day. Also keep an eye out for a special appearance by Miss Molly Moon at the Scott M. Hammer Workshop for New Researchers and Trainees on Sunday, February 22.


2/26: Brian has been participating in a think tank organized by AVAC focused on future options for HIV post-exposure prophylaxis (PEP). The group will have its first in-person meeting in Denver following CROI.


The Latinx Caucus has an abstract accepted to the NaLa Conference in April and are looking forward to sharing our work!
Follow Legacy Project on Social Media!
TIKTOK
INSTAGRAM
FACEBOOK
BLUESKY
 
 
February 22 - 25, 2026
CROI 2026 (Denver, Colorado, USA)
March 16 - 18, 2026
AIDSWatch 2026 (Washington DC, USA)
April 8-10, 2026
Biomedical HIV Prevention Summit (BHPS) (Chicago, Illinois, USA)
April 21-23, 2026
2026 NaLa Conference (Dallas, Texas, USA)
May 6 - 8, 2026
HVTN Annual Network Meeting (Washington DC, USA)
May 16 - 20, 2026
HPTN Annual Meeting
June 9 - 11, 2026
IMPAACT Annual Meeting (Virtual)
June 9 - 11, 2026
Continuum 2026 (San Juan, Puerto Rico)
June 23 - 28, 2026
ACTG Annual Meeting
July 25 - 30, 2026
AIDS 2026 (Rio de Janeiro, Brazil)
September 17 - 20, 2026
2026 U.S. Conference on HIV/AIDS (Anaheim, California, USA)
VIEW ALL UPCOMING EVENTS



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